Why should Comfora be prescribed for Interstitial Cystitis?
Comfora (Pentosan PolysufateSodium) is effective in improving the symptoms of patients
suffering from IC and provides relief from pain and discomfort.
This is the only FDA-approved drug taken orally for bladder pain and discomfort.
The usual dosage is 100-mg capsules thrice daily.
The exact mechanism of function of Comfora is not clearly understood. There are several proposed theories by
which Comfora is thought to function. It is believed that the drug could repair
and heal the damaged parts of the GAG layer in the bladder.
Several studies have shown that a minimum duration of 6 months to 1 year is necessary to provide moderate symptom relief.
Therefore, doctors must encourage the patients to continue the medications for adequate period of time.
The safety of the drug in children and adolescents below the age of 18 years has not yet been established.Very mild adverse events were noted, such as nausea, loss of hair, rashes, headaches and loose motion. Comfora must be administered with caution in patients with bleeding disorders, liver and spleen
insufficiencies. Hence, it is very important to inform your doctor about all the previous ailments, and previous and current medications.