Who out there is not worried about their money? Elmiron is burning a big-hole in
the pockets of the patients. When you have a chronic illness like IC, money
Comfora is orally bioavailable Pentosan Polysulfate Sodium.
Its mechanism of action is thought to be adherence to the bladder surface
supplementing the defective natural glycosaminoglycan layer. It is hypothesized
that this action ameliorates the symptoms of interstitial cystitis. Orally
administered pentosan has a urinary excretion half-life of 4.4 hours for the
unchanged drug. A single dose is completely eliminated in 144 hours.
The recommended dose is 300 mg/day taken as one 100 mg capsule orally 3 times
daily. The capsules should be taken with water at least 1 hour before meals or 2
hours after meals
Some patients with interstitial cystitis may require 6 to 8 weeks of therapy
with pentosan to achieve relief of symptoms. Long-term continuation of pentosan
therapy is necessary for persistent therapeutic effect.
Elmiron and Comfora only differ in their price tag. Elmiron placed at a higher
value is not affordable by all. Swati Spentose Pvt. Ltd. took the initiative in
launching the only Indian Brand- Comfora. large segment of patients, for whom it was difficult to afford Elmiron can now
buy it and lead a comforting life even during IC.
The next issue will cover the All-India USICONS held at the capital as well as
the regional USICONS attended by our expert staff.
The symptoms in women exacerbate just before or during menstruation,
during ovulation or if they are taking contraceptive pills. It should be emphasized, however,
that many patients never progress further than a relatively mild form of IC.